Publications

1. Decoster L, Trova S, Zucca S, Bulk J, Gouveia A, Ternier G, (...) Silva MSB* & Giacobini P*. A GnRH neuronal population in the olfactory bulb translates socially relevant odors into reproductive behavior in male mice. Nat Neurosci 2024;27:1758–73. https://doi.org/10.1038/s41593-024-01724-1. (* = co-last authorship).
2. Fernandois D, Rusidzé M, Mueller-Fielitz H, Sauve F, Deligia E, Silva MSB, et al. Estrogen receptor-α signaling in tanycytes lies at the crossroads of fertility and metabolism. Metabolism 2024;158. https://doi.org/10.1016/j.metabol.2024.155976.
3. Silva MSB, Decoster L, Delpouve G, Lhomme T, Ternier G, Prevot V, et al. Overactivation of GnRH neurons is sufficient to trigger polycystic ovary syndrome-like traits in female mice. EBioMedicine 2023;97:104850. https://doi.org/10.1016/j.ebiom.2023.104850.
4. Silva MSB, Navarro VM, Chachlaki K. Editorial: The neuroendocrine female brain: from normal reproductive function to disease. Front Neurosci 2023;17. https://doi.org/10.3389/fnins.2023.1243349.
5. Barbotin AL, Mimouni NEH, Kuchcinski G, Lopes R, Viard R, Rasika S, Manzur D, Silva MSB, et al. Hypothalamic neuroglial plasticity is regulated by anti-Müllerian hormone and disrupted in polycystic ovary syndrome. EBioMedicine 2023;90. https://doi.org/10.1016/j.ebiom.2023.104535.
6. Silva MSB, Decoster L, Trova S, Mimouni NEH, Delli V, Chachlaki K, et al. Female sexual behavior is disrupted in a preclinical mouse model of PCOS via an attenuated hypothalamic nitric oxide pathway. Proc Natl Acad Sci U S A 2022;119. https://doi.org/10.1073/pnas.2203503119.
7. Manfredi-Lozano M, Leysen V, Adamo M, Paiva I, Rovera R, Pignat J-M, Timzoura FE, Candlishet M, Eddarkaouial S, Malone S, Silva MSB, et al. GnRH replacement rescues cognition in Down syndrome. Science 2022;377. https://doi.org/10.1126/SCIENCE.ABQ4515.
8. Uk A, Decanter C, Grysole C, Keller L, Béhal H, Silva MSB, et al. Polycystic ovary syndrome phenotype does not have impact on oocyte morphology. Reprod Biol Endocrinol 2022;20. https://doi.org/10.1186/s12958-021-00874-2.
9. Silva MSB, Campbell RE. Polycystic Ovary Syndrome and the Neuroendocrine Consequences of Androgen Excess. Compr Physiol 2022;12:3347–69. https://doi.org/10.1002/cphy.c210025.
10. Delli V, Silva MSB, Prévot V, Chachlaki K. The KiNG of reproduction: Kisspeptin/ nNOS interactions shaping hypothalamic GnRH release. Mol Cell Endocrinol 2021;532:111302. https://doi.org/10.1016/j.mce.2021.111302.
11. Nair BB, Khant Aung Z, Porteous R, Prescott M, Glendining KA, Jenkins DE, Augustine RA, Silva MSB, et al. Impact of chronic variable stress on neuroendocrine hypothalamus and pituitary in male and female C57BL/6J mice. J Neuroendocrinol 2021;33. https://doi.org/10.1111/jne.12972.
    
12. Silva MSB, Giacobini P. New insights into anti-Müllerian hormone role in the hypothalamic–pituitary–gonadal axis and neuroendocrine development. Cell Mol Life Sci 2021;78. https://doi.org/10.1007/s00018-020-03576-x.
13. Silva MSB, Desroziers E, Hessler S, Prescott M, Coyle C, Herbison AE, et al. Activation of arcuate nucleus GABA neurons promotes luteinizing hormone secretion and reproductive dysfunction: Implications for polycystic ovary syndrome. EBioMedicine 2019;44:582–96. https://doi.org/10.1016/j.ebiom.2019.05.065.
14. Silva MSB, Giacobini P. Don't Trust Your Gut: When Gut Microbiota Disrupt Fertility. Cell Metab 2019;30:616–8. https://doi.org/10.1016/j.cmet.2019.09.005.
15. Silva MSB, Prescott M, Campbell RE. Ontogeny and reversal of brain circuit abnormalities in a preclinical model of PCOS. JCI Insight 2018;3:pii: 99405. https://doi.org/10.1172/jci.insight.99405.
16. Brasil GA, Lima EM de, Nascimento AM do, Caliman IF, Medeiros ARS de, Silva MSB, et al. Nandrolone decanoate induces cardiac and renal remodeling in female rats, without modification in physiological parameters: The role of ANP system. Life Sci 2015;137:65–73. https://doi.org/10.1016/j.lfs.2015.07.005.
17. Lindsey SH, da Silva AS, Silva MS, Chappell MC. Reduced vasorelaxation to estradiol and G-1 in aged female and adult male rats is associated with GPR30 downregulation. Am J Physiol Endocrinol Metab 2013;305:E113-8. https://doi.org/10.1152/ajpendo.00649.2012.
18. Yamaleyeva LM, Pulgar VM, Lindsey SH, Yamane L, Varagic J, McGee C, DaSilva M, et al. Uterine artery dysfunction in pregnant ACE2 knockout mice is associated with placental hypoxia and reduced umbilical blood flow velocity. Am J Physiol Endocrinol Metab 2015;309:E84-94. https://doi.org/10.1152/ajpendo.00596.2014.